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Document ID ca-gcdwqgtd-2015-03-10-2 Title Guidelines for Canadian Drinking Water Quality: Guideline Technical Document – 1,2–Dichloroethane URL https://www.canada.ca/en/health-canada/services/publications/healthy-living/guidelines-canadian-drinking-water-quality-guideline-technical-document-1-2-dichloroethane/page-3-guidelines-canadian-drinking-water-quality-guideline-technical-document-1-2-dichloroethane.html Jurisdiction /ca Subdomain(s) Drinking water, Water quality standards Language en Status completed Analyzed at 2026-03-18 13:24:04.671134+00:00 Relevance Technical guideline for 1,2-Dichloroethane in Canadian drinking water.

Q Qualitative Requirements (18)

Req ID Category Intent Legal Status Name Subdomain(s) Context Conditions Confidence
#Q001operationaloperationalrecommendedConsideration of operational problems for combined technologiesdrinking waterThe common operational problems existing with PTA systems and GAC adsorption contactors are similar and should be considered when these combined technologies are employed.When combining aeration technologies and GAC into a two-step treatment train.high
#Q002designtreatmentrecommendedConsideration of by-product formation during advanced oxidationdrinking waterThe formation of by-products from the oxidation and/or advanced oxidation of 1,2-DCA or other inorganic or organic compounds in the source water should be considered when using these processes.When using advanced oxidation processes (combinations of chemical oxidants, UV light and catalysts) for water treatment.high
#Q003treatmenttreatmentrecommendedAvoidance of additional residential treatment for municipally treated waterdrinking waterGenerally, it is not recommended that drinking water treatment devices be used to provide additional treatment to municipally treated water.When an individual household receives municipally treated water.high
#Q004treatmenthealthrecommendedUse of certified drinking water treatment devicesdrinking waterHealth Canada does not recommend specific brands of drinking water treatment devices, but it strongly recommends that consumers use devices that have been certified by an accredited certification body as meeting the appropriate NSF International/ American National Standards Institute (ANSI) drinking water treatment unit standards.When consumers use residential drinking water treatment devices.high
#Q005designtreatmentrecommendedPreference for point-of-entry treatment systemsdrinking waterPoint-of-entry systems are preferred for VOCs such as 1,2-DCA, because they provide treated water for bathing and laundry as well as for cooking and drinking.When choosing a residential filtration system for VOC removal.high
#Q006monitoringtreatmentrecommendedPeriodic testing of residential treatment devicesdrinking waterPeriodic testing by an accredited laboratory should be conducted on both the water entering the treatment device and the water it produces to verify that the treatment device is effective.When using a residential drinking water treatment device.high
#Q007operationaloperationalrecommendedAdherence to manufacturer instructions for treatment devicesdrinking waterConsumers should follow the manufacturer's instructions regarding the expected longevity of the components in their treatment device.When operating and maintaining residential drinking water treatment devices.high
#Q008administrativehealthmandatoryOngoing monitoring of new research by Health Canadadrinking waterAs part of its ongoing guideline review process, Health Canada will continue to monitor new research in this area and recommend any change(s) to the guideline that it deems necessary.high
#Q009treatmenttreatmentmandatoryPretreatment requirement for GAC contactorsdrinking waterTo prevent the bed from clogging, pretreatment of the water before it enters the GAC contactor is often required (Snoeyink, 1990; Speth, 1990; AWWA, 1991; Crittenden et al., 2005).When using GAC adsorption contactors for water treatment.high
#Q010treatmenttreatmentguidanceOff-gas treatment for PTAdrinking waterAs PTA transfers VOCs from water to air, treatment of the stripping tower off-gas to reduce the contaminant concentrations prior to discharge into the atmosphere may be necessary (Crittenden et al. 1988; Adams and Clark, 1991).When using Packed Tower Aeration (PTA) to transfer VOCs from water to air.high
#Q011designtreatmentrecommendedSite considerations for PTA installationdrinking waterAlthough the PTA process is effective, site considerations such zoning, column height and noise restrictions should be considered.When planning the installation of a Packed Tower Aeration system.high
#Q012treatmenttreatmentguidancePost-treatment for aeration processesdrinking waterPost treatment, such as the use of a corrosion inhibitor, may also be required to reduce corrosive properties of the water due to increased dissolved oxygen from the aeration process.Following the aeration process in water treatment.high
#Q013treatmenttreatmentmandatoryPretreatment requirement for RO membranesdrinking waterA pretreatment of the feed water is required to prevent scaling and fouling of the RO membranes.When using Reverse Osmosis (RO) systems for water treatment.high
#Q014treatmentoperationalguidanceResidential influent pretreatmentdrinking waterA consumer may need to pretreat the influent water to reduce the fouling and extend the service life of the membrane.When a consumer operates a point-of-use reverse osmosis (RO) system.high
#Q015operationaloperationalguidanceOperating considerations for GAC adsorption contactorsdrinking waterOperating considerations may include a need to ensure a proper backwash, maintain the bed depth and bed density after backwashing and control the flow rate.When operating granular activated carbon (GAC) adsorption contactors.high
#Q016operationaloperationalguidanceOperation of multi-bed GAC systemsdrinking waterIn systems with multiple beds, the individual beds can be operated beyond the time of initial breakthrough, provided the blended effluent is still below the guideline value.In GAC systems utilizing multiple beds.high
#Q017operationaloperationalguidanceMethods to prevent PTA column foulingdrinking waterMethods to prevent the fouling of the column include pH suppression of the influent, using scale inhibitors or iron removal prior to the PTA application.When using Packed Tower Aeration (PTA) systems to prevent fouling.high
#Q018designtreatmentguidanceDesign of residential POE systems using certified materialsdrinking waterIn the case where certified point-of-entry treatment devices are not available for purchase, systems can be designed and constructed from certified materials.When certified point-of-entry devices are unavailable.high

P Quantitative Requirements (44)

Req ID Category Intent Legal Status Name Subdomain(s) Limit Type Limit Value Context Conditions Confidence
#P001chemicalhealthmandatory1,2-Dichloroethanedrinking waterMAC0.005 mg/LConsequently, a MAC of 0.005 mg/L (5 µg/L) for 1,2-DCA is establishedBased on an estimated lifetime excess risk of cancers of 10-6high
#P002chemicalhealthmandatory1,2-Dichloroethanedrinking waterMAC5 µg/LConsequently, a MAC of 0.005 mg/L (5 µg/L) for 1,2-DCA is establishedBased on an estimated lifetime excess risk of cancers of 10-6high
#P003designtreatmentmandatory1,2-DCA (NSF/ANSI Standard 53)drinking waterrequirement0.005 mg/LFor a drinking water treatment device to be certified to NSF/ANSI Standards 53 for the reduction of 1,2-DCA alone, the device must be capable of reduction an average influent concentration of 0.015 mg/L to a maximum of 0.005 mg/L.Certification to NSF/ANSI Standard 53 for reduction of 1,2-DCA alonehigh
#P004designtreatmentmandatory1,2-DCA (NSF/ANSI Standard 53 surrogate testing)drinking waterrequirement0.0048 mg/LFor a drinking water treatment device to be certified to NSF/ANSI Standards 53 by surrogate testing, the device must be capable of reduction of an influent concentration of 0.088 mg/L 1,2-DCA to a maximum product water concentration of 0.0048 mg/LCertification to NSF/ANSI Standard 53 by surrogate testinghigh
#P005designtreatmentmandatory1,2-DCA (NSF/ANSI Standard 58 surrogate testing)drinking waterrequirement0.0048 mg/LFor a drinking water treatment device to be certified to NSF/ANSI Standards 58 by surrogate testing, the device must be capable of a 95% reduction of 1,2-DCA, from an influent concentration of 0.088 mg/L to a maximum of 0.0048 mg/LCertification to NSF/ANSI Standard 58 by surrogate testing (reverse osmosis)high
#P006chemicalhealthguidance1,2-Dichloroethane (Non-cancer HBV)drinking watertreatment_goal0.26 mg/LThe HBV for 1,2-DCA in drinking water for non-cancer effects is derived as follows: HBV = [0.078 mg/kg bw/day × 70 kg × 0.20] / 4.2 L-eq/day = 0.26 mg/L (260 µg/L)Based on renal tubular regeneration in female F344 ratshigh
#P007chemicalhealthguidance1,2-Dichloroethane (Cancer HBV - 10-5 risk)drinking watertreatment_goal0.05 mg/LTable 4: HBV based on the three different estimated risk levels. 10-5 risk level: 0.05 mg/LBased on lifetime excess risk of 10-5high
#P008chemicalhealthguidance1,2-Dichloroethane (Cancer HBV - 10-4 risk)drinking watertreatment_goal0.5 mg/LTable 4: HBV based on the three different estimated risk levels. 10-4 risk level: 0.5 mg/LBased on lifetime excess risk of 10-4high
#P009designtreatmentguidelineBAT 1,2-DCA Removal Efficiencydrinking watertreatment_goal99 %The U.S. EPA has identified packed tower aeration (PTA) and granular activated carbon (GAC) as the best available technologies (BATs) for 1,2-DCA removal in drinking water and the agency considers a 99% reduction to be achievable under all anticipated conditionsUsing PTA or GAC technologieshigh
#P010operationalreportingmandatory1,2-Dichloroethane Practical Quantitation Level (PQL)drinking waterrequirement5 µg/LThe current U.S. EPA practical quantitation level (PQL) for 1,2-DCA is 5 µg/L.high
#P011operationalreportingguidanceMinimum Quantitation Level (Method SM 6200B)drinking waterrequirement0.22 µg/LThe minimum quantitation levels, defined as the lowest level that can be quantified accurately, are 0.22 µg/L and 0.296 µg/L for methods SM 6200B and SM 6200C respectively.Defined as the lowest level that can be quantified accuratelyhigh
#P012operationalreportingguidanceMinimum Quantitation Level (Method SM 6200C)drinking waterrequirement0.296 µg/LThe minimum quantitation levels, defined as the lowest level that can be quantified accurately, are 0.22 µg/L and 0.296 µg/L for methods SM 6200B and SM 6200C respectively.Defined as the lowest level that can be quantified accuratelyhigh
#P013operationalreportingguidanceEstimated Quantitation Level (EQL)drinking waterrequirement0.5 µg/LEPA retained 0.5 µg/L as an estimated quantitation level (EQL) for 1,2-DCA which is an estimate of the possible lower bound for a PQL and take into consideration laboratory analytical limits nationwideEstimate of the possible lower bound for a Practical Quantitation Level (PQL)high
#P014designtreatmentmandatoryNSF/ANSI Standard 58 Reduction Efficiencydrinking waterrequirement95 %For a drinking water treatment device to be certified to NSF/ANSI Standards 58 by surrogate testing, the device must be capable of a 95% reduction of 1,2-DCA, from an influent concentration of 0.088 mg/L to a maximum of 0.0048 mg/LCertification to NSF/ANSI Standard 58 by surrogate testinghigh
#P015operationalhealthmandatoryExposure Significance Thresholddrinking waterrequirement10 %Both the dermal and inhalation routes of exposure for a VOC are considered significant if they contribute at least 10% of the drinking water consumption levelApplicable to VOC exposure assessmenthigh
#P016operationalhealthmandatoryStandard Canadian Drinking Water Consumption Ratedrinking waterrequirement1.5 L/daystandard Canadian drinking water consumption rate of 1.5 L/dayUsed in multi-route exposure assessmenthigh
#P017operationalhealthmandatoryTotal Litre-equivalent Daily Exposure (1,2-DCA)drinking waterrequirement4.2 L-eq/daytotal litre-equivalent daily exposure to 1,2-DCA in drinking water was estimated to be 4.2 L-eq (rounded)Accounting for multiroute exposure using PBPK modelhigh
#P018operationalreportingmandatoryMethod Detection Limit (MDL) - Method 502.2drinking waterrequirement0.03 µg/LMethod 502.2 revision 2.1... has a method detection limit (MDL) of 0.03 µg/L.Using electrolytic conductivity detector (ELCD) and photoionization detector (PID) in serieshigh
#P019operationalreportingmandatoryMethod Detection Limit (MDL) - Method 524.3drinking waterrequirement0.025 µg/LMethod 524.3 is an updated version of method 524.2 and has a detection limit of 0.025 µg/L.Optimization of purge-and-trap parametershigh
#P020operationalreportingmandatoryMethod Detection Limit (MDL) - Method 524.2drinking waterrequirement0.02 - 0.06 µg/LDepending on the GC column and GC/MS interface used, the method has an MDL range of 0.02 - 0.06 µg/L (U.S. EPA, 1995, 2009a).Interfaced to a mass spectrometer (MS)high
#P021operationalreportingguidanceMethod Detection Limit (MDL) - SM 6200Bdrinking waterrequirement0.055 µg/LMethod SM 6200B has a MDL of 0.055 µg/Lhigh
#P022operationalreportingguidanceMethod Detection Limit (MDL) - SM 6200Cdrinking waterrequirement0.074 µg/LSM 6200C has a MDL of 0.074 µg/L.high
#P023chemicalhealthguidanceTolerable Daily Intake (TDI)drinking watertreatment_goal0.078 mg/kg bw/dayTDI = [78 mg/kg bw/day] / 1000 = 0.078 mg/kg bw/dayBased on BMDL10 for renal tubular regeneration and uncertainty factor of 1000high
#P024operationalhealthguidanceSignificance Threshold - Skin Permeability Coefficient (Kp)drinking waterrequirement> 0.024 cm/hFor a tier 1 goal of 0.15 L-eq, the skin permeability coefficient (Kp) for 1,2-DCA should be higher than 0.024 cm/h (Krishnan and Carrier, 2008).To determine if dermal route of exposure contributes a minimum of 10% of consumption levelhigh
#P025operationalhealthguidanceSignificance Threshold - Air:Water Concentration Factor (Fair:water)drinking waterrequirement> 0.00063 ratiofor a tier 1 goal of 0.15 L-eq, the average ratio of air to water 1,2-DCA concentration factor (Fair:water) should be greater than 0.00063To determine if inhalation route contributes at least 10% of consumption levelhigh
#P026operationalhealthguidanceDermal Exposure (L-eq) - PBPK Approachdrinking waterrequirement2.06 L-eqthe litre-equivalent contributions for dermal and inhalation exposure were determined to be 2.06 and 0.68 L-eq, respectively.Calculated using human PBPK model for a 30-minute bathing scenariohigh
#P027operationalhealthguidanceInhalation Exposure (L-eq) - PBPK Approachdrinking waterrequirement0.68 L-eqthe litre-equivalent contributions for dermal and inhalation exposure were determined to be 2.06 and 0.68 L-eq, respectively.Calculated using human PBPK model for a 30-minute bathing scenariohigh
#P028chemicalhealthguidance1,2-Dichloroethane (Non-cancer HBV - µg/L)drinking watertreatment_goal260 µg/LThe HBV for 1,2-DCA in drinking water for non-cancer effects is derived as follows: HBV = 0.26 mg/L (260 µg/L)Based on renal tubular regenerationhigh
#P029operationalreportingguidancePotential Practical Quantitation Level (PQL) Rangedrinking waterrequirement0.3 - 0.6 µg/LThe agency determined that the assessment data supported the reduction of the PQL and estimated a lower possible PQL in the range of 0.3 to 0.6 µg/L.Supported by U.S. EPA assessment of performance evaluation datahigh
#P030operationalhealthguidanceTotal Daily Exposure (Conservative Approach)drinking waterrequirement4.6 L-eq/dayAssuming one showering or bathing event per day and adding these values to the standard Canadian drinking water consumption rate of 1.5 L/day, this results in a total daily exposure of 4.6 L-eq (rounded from 4.56 L-eq).Using two-tier approach (1.63 L-eq dermal and 1.43 L-eq inhalation)high
#P031chemicalhealthguidance1,2-Dichloroethane (Cancer HBV - 10-6 risk)drinking watertreatment_goal0.005 mg/LTable 4: HBV based on the three different estimated risk levels. 10-6 risk level: 0.005 mg/LBased on lifetime excess risk of 10-6high
#P032operationalhealthguidanceDermal Exposure (L-eq) - Two-tier Approachdrinking waterrequirement1.63 L-eqUsing the two-tier approach, the litre-equivalent were calculated as 1.63 L-eq for the dermal routeCalculated based on skin permeability coefficient of 0.259 cm/hhigh
#P033operationalhealthguidanceInhalation Exposure (L-eq) - Two-tier Approachdrinking waterrequirement1.43 L-eqUsing the two-tier approach, the litre-equivalent were calculated as... 1.43 L-eq for the inhalation route.Based on calculated air:water concentration factor of 0.00604high
#P034designtreatmentmandatoryNSF/ANSI Standard 53 Influent Challenge Concentrationdrinking waterrequirement0.015 mg/Lthe device must be capable of reduction an average influent concentration of 0.015 mg/L to a maximum of 0.005 mg/L.Certification to NSF/ANSI Standard 53 for 1,2-DCA alonehigh
#P035designtreatmentmandatoryNSF/ANSI Standard 53/58 Surrogate Influent Challenge Concentrationdrinking waterrequirement0.088 mg/Lthe device must be capable of reduction of an influent concentration of 0.088 mg/L 1,2-DCA to a maximum product water concentration of 0.0048 mg/LCertification by surrogate testinghigh
#P036operationalhealthguidanceStandard Adult Exposed Skin Areadrinking waterrequirement18000 cm2A is the area of skin exposed, assumed to be 18 000 cm2 for adultsUsed in multi-route dermal exposure calculationshigh
#P037operationalhealthguidanceAdult Alveolar Ventilation Ratedrinking waterrequirement675 L/hQalv is the adult alveolar ventilation rate, assumed to be 675 L/hUsed in multi-route inhalation exposure calculationshigh
#P038operationalhealthguidanceStandard Adult Body Weightdrinking waterrequirement70 kg70 kg is the average body weight of an adultUsed in health-based value (HBV) derivationshigh
#P039operationalhealthmandatoryAllocation Factor (Drinking Water)drinking waterrequirement0.20 dimensionlessfloor allocation factor (20%) of the daily intake allocated to drinking waterUsed in the calculation of the MAC and HBVhigh
#P040operationalhealthmandatoryUncertainty Factor (TDI Derivation)drinking waterrequirement1000 dimensionless1000 is the uncertainty factorApplied to BMDL10 for renal tubular regenerationhigh
#P041chemicalhealthguidancePoint of Departure (BMDL10)drinking waterrequirement78 mg/kg bw/day78 mg/kg bw/day is the BMDL10 for renal tubular regeneration in female F344 ratsPoint of departure for non-cancer risk assessmenthigh
#P042chemicalhealthguidanceHuman External Dose (10-6 Risk Level)drinking watertreatment_goal0.0003 mg/kg bw/dayTable 3: Humans (PBPK approach) 10-6 risk level: 0.0003 mg/kg bw/dayCancer external human dose based on PBPK approachhigh
#P043chemicalhealthguidanceHuman External Dose (10-5 Risk Level)drinking watertreatment_goal0.003 mg/kg bw/dayTable 3: Humans (PBPK approach) 10-5 risk level: 0.003 mg/kg bw/dayCancer external human dose based on PBPK approachhigh
#P044chemicalhealthguidanceHuman External Dose (10-4 Risk Level)drinking watertreatment_goal0.03 mg/kg bw/dayTable 3: Humans (PBPK approach) 10-4 risk level: 0.03 mg/kg bw/dayCancer external human dose based on PBPK approachhigh

D Definitions (77)

Req ID Category Name Context Confidence
#D0011,2-Dichloroethane1,2-DCAhigh
#D002volatile organic compoundVOChigh
#D003physiologically based pharmacokineticPBPKhigh
#D004electrolytic conductivity detectorELCDhigh
#D005photoionization detectorPIDhigh
#D006mass spectrometerMShigh
#D007selected ion monitoringSIMhigh
#D008practical quantitation levelPQLhigh
#D009estimated quantitation levelEQLhigh
#D010minimum quantitation levelsdefined as the lowest level that can be quantified accuratelyhigh
#D011packed tower aerationPTAhigh
#D012granular activated carbonGAChigh
#D013best available technologiesBATshigh
#D014powder activated carbonPAChigh
#D015natural organic matterNOMhigh
#D016empty bed contact timeEBCThigh
#D017Initial breakthroughdefined as the time when the contaminant concentration in the effluent exceeds the treatment objectivehigh
#D018reverse osmosisROhigh
#D019ultravioletUVhigh
#D020Standards Council of CanadaSCChigh
#D021body weightbwhigh
#D022glutathioneGSHhigh
#D023deoxyribonucleic acidDNAhigh
#D024ribonucleic acidRNAhigh
#D025glutathione transferaseGSThigh
#D026median lethal concentrationLC50high
#D027median lethal doseLD50high
#D028no-observed-effect concentrationNOEChigh
#D029no-observed-effect levelsNOELshigh
#D030no-observed-adverse-effect levelNOAELhigh
#D031lowest-observed-adverse-effect levelLOAELhigh
#D032maximum tolerated doseMTDhigh
#D033benchmark doseBMDhigh
#D034health-based valueHBVhigh
#D035tolerable daily intakeTDIhigh
#D036lower confidence limit of the benchmark doseBMDLhigh
#D037suitable BMDLdefined as a lower 95% confidence limit estimate of dose corresponding to a 1-10% level of risk over background levels.high
#D038maximum contaminant levelMCLhigh
#D039public health goalPHGhigh
#D040litre-equivalentsL-eqhigh
#D041skin permeability coefficientKphigh
#D042average ratio of air to water 1,2-DCA concentration factorFair:waterhigh
#D043Henry's Law constantKawhigh
#D044adult alveolar ventilation rateQalvhigh
#D045method detection limitMDLhigh
#D046Advanced oxidation processesrefer to the use of combinations of chemical oxidants, ultraviolet (UV) light and catalysts (e.g., O3/H2O2, O3/UV; UV/ H2O2; UV/TiO2; O3/UV/TiO2; O3 oxidation at elevated pH) to generate highly reactive radicals such as hydroxyl radicals, which are strong oxidants and react rapidly and non-selectively with organic contaminants.high
#D047American National Standards InstituteANSIhigh
#D048fraction of dose absorbedFabshigh
#D049area of skin exposedAhigh
#D050conversion factorCfhigh
#D0519000 × g rat liver supernatantS9high
#D052time-weighted averageTWAhigh
#D053ethylene dichloride1,2-dichloroethane (also known as)high
#D054floor allocation factordefault proportion (20%) of the daily intake allocated to drinking waterhigh
#D055tduration of the shower or bathhigh
#D056thiodiglycolic acidthiodiacetic acid (also called)high
#D057Integrated Risk Information SystemIRIShigh
#D058gas chromatographyGChigh
#D059half sulphur mustardS-(2-chloroethyl)-glutathionehigh
#D060International Agency for Research on CancerIARChigh
#D061World Health OrganizationWHOhigh
#D062microsomal oxidative pathwayalso known as cytochrome P450-mediated and mixed-function oxidase pathwayhigh
#D063direct conjugation or GSH conjugation pathwayalso known as GSH-dependent cytosolic pathwayhigh
#D064leukocytosisincreases in white blood cellshigh
#D065gem-chlorohydrinunstable reactive intermediatehigh
#D066glutathione episulfonium ionan alkylating agenthigh
#D067BMD10benchmark dose corresponding to a 10% increase in extra risk over background levelshigh
#D068BMDL10lower 95% confidence limit estimate of the benchmark dose corresponding to a 10% increase in extra risk over background levelshigh
#D069Standard methodsSMhigh
#D070Office of Environmental Health Hazard AssessmentOEHHAhigh
#D071National Cancer InstituteNCIhigh
#D072Canadian Chemical Producers' AssociationCCPAhigh
#D073Alberta Environmental CentreAEChigh
#D074Agency for Toxic Substances and Disease RegistryATSDRhigh
#D075International Association of Plumbing & Mechanical OfficialsIAPMOhigh
#D076Water Quality AssociationWQAhigh
#D077California Department of Health ServicesCDHShigh